Antigen-antibody interaction. The immunodominant region of EDP208 pili.
نویسندگان
چکیده
منابع مشابه
Antibody molecules and the antigen-antibody interaction
The immune system is a diffuse organ dispersed in the body and basically constitutes lymphoid cells, cytokine and antibody molecules. The latter are the product of lymphoid cells. In the past, the cellular basis for antibody formation was the subject of several theories, e.g., the selective theory according to P EHRLICH (1900), the instructive antigen-template theories as suggested by L PAULING...
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Despite the high specificity between antigen and antibody binding, similar epitopes can be recognized or cross-neutralized by paratopes of antibody with different binding affinities. How to accurately characterize this slight variation which may or may not change the antigen-antibody binding affinity is a key issue in this area. In this report, by combining cylinder model with shell structure m...
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A gonococcal pili antigen preparation was used to detect antibody activity sera obtained from 322 culture-positive asymptomatic females and 150 negative controls. Pili were obtained from a culture of type 2 Neisseria gonorrhoeae (strain 2686) and labeled with 125I for use in a double-antibody radioimmunoassay test system. Of the 322 sera obtained from culture-positive, asymptomatic females, 276...
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Adult Onchocerca voluvlus and infective larvae, but not microfilariae contain an immunodominant antigen (33,000 and 21,000 Mr in females, 39,000, 33,000, and 21,000 Mr in males, 133,000 Mr in infective larvae) which is recognized by an Onchocerca-specific mAb. The component is part of the reproductive organs and muscles. 96.2% of onchocerciasis sera contained antibodies detectable by immunoblot...
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Protective immuni ty against several species of malar ia parasites has been obtained by vaccinat ion with x-irradiated sporozoites (reviewed in reference 1). The serum of protected animals reacts with the surface membrane of sporozoites and neutralizes their infectivity, which suggests that the effect of the vaccine is at least in part an t ibody mediated. T he membrane-associated protective an...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1985
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(20)71190-7